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Response/Signaling Feedback Models for Cell Cycle Clustering and Quorum Sensing

Tuesday, November 5, 2013 at 4:30pm to 5:30pm

King Building, 239 10 North Professor Street, Oberlin, OH 44074

A talk by Richard Buckalew of Ohio University. 

Examples of cell cycle synchronization and clustering are abundant in nature, and mathematical modeling has proven to be a fruitful avenue of investigation into these phenomena.  In this talk I will present a family of models called Response/Signaling (RS) that have recently been shown to reproduce a number of observed behaviors using a very simple framework.  An RS model is a simple coupled-oscillator model with phase dependent feedback, and such models can lead to complex emergent behavior, for example quorum sensing, similar to what we see in laboratory yeast populations.  It is hoped that these models will prove useful for understanding the synchrony and division wave phenomena observed in drosophila and zebrafish embryogenesis as well.

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Mathematics, Academic

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Cathy Murillo

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